How
would you measure the force that a human
cell applies to its surroundings?
How
would you measure the attachment force
between cells?
How would you determine how cells sense their mechanical
environment?
Come
to the Annual ASME / SWE Steak Roast
20 October 2005
Mendon Ponds Park
Consider this human cell. Looks simple to work with, right?!!?
Here is an actual 'picture' of a human cell.
We all have seen images of red blood cells. Dr. King will talk about
how blood cells adhere to the vessel wall. He will detail the forces,
the magnitude of the forces, and how to measure them.
More complicated systems include branching.
Here is a velocity plot.
ABSTRACT of Presentation by Michael R.
King, Ph.d.:
Bioengineering
in general, and cellular engineering specifically, is necessarily
interdisciplinary: combining tools and ideas from the fields of
biology,
engineering, applied mathematics, physics and chemistry. Research
engineers and
scientists converge on cellular engineering from several different
directions:
cell and molecular biologists looking for new ways to quantify and
model their
results, engineers from traditional disciplines (chemical, electrical,
mechanical) with an interest in tackling biomedically important
problems, and
of course bioengineers specializing in cell & tissue engineering
applications.
In this talk, I review some interesting recent work by several
laboratories to
probe the mechanics of living cells. Methods have been developed to
measure the
forces which cells exert on their surroundings, unlock the mysteries of
how
cells sense their mechanical environment, and quantify the strength of
physical
attachments between neighboring cells. The work of my own laboratory
focuses on
using engineering tools to predict how and when flowing blood cells
will adhere
to surrounding surfaces such as the vessel wall, and to identify which
physical
factors can be varied to reduce or restore adhesive function. Finally,
I will
discuss our laboratory's approach of using this fundamental knowledge
of cell
adhesion to purify stem cells taken from adult bone marrow, for use in
cancer
therapy.
Dr. Michael R. King is an Assistant Professor at the University of Rochester in the
Departments of Biomedical
Engineering and Chemical
Engineering.
Mendon Ponds Park's West Lodge on Canfield Road. A map
can be found at http://www.monroecounty.gov/documentView.asp?docID=33
Registration and Snacks: 5:00 p.m.
Dinner: 6:00 p.m.
Program: 7:00 p.m.
Menu
Hors d'oeuvre
Cheese and Crackers, Fresh Vegetables with Dip
Dinner
8 oz Steak
8
oz Chicken Breast
Potato
Salad
Marconi
Salad
Garden
Salad
Dinner
Rolls
Beverages
Coffee
Tea
Beer
Pop
(Soda)
Water
Cider
Dessert
Cookies
Please reserve your place either on Pay Pal using the links below or by
mailing a check to Bob Ellson, 20 Dartford Road, Rochester, New York,
14618. Registration deadline is 17 October 2005 at midnight Eastern
time.
SWE Students Registered. $5
SWE Senior Members. $15
ASME Students with ID. $5
ASME Senior Members. $15
All Others. $15
Questions will be answered by return email from rochesterny@asme.org or johnamon@asme.org
Return to the Rochester New York
Senior Section
homepage,
Update your email and/or postal
mailing address on ASME's online roster database
here.
Visit our
Community
of Practice
A
full
list of your Executive Committee members is available for your
reference including meeting dates.
For information, send an email to us at
RochesterNY@asme.org
